| 产品编号 | bs-104433P |
| 英文名称 | Recombinant Human ADCY6 Protein, N-His |
| 中文名称 | |
| 别 名 | Adenylate cyclase type 6; KIAA0422; ATP pyrophosphate-lyase 6; ADCY6; Adenylyl cyclase 6; Ca(2+)-inhibitable adenylyl cyclase; Adenylate cyclase type VI |
| 克 隆 号 | |
| 理论分子量 | 25.41 kDa |
| 性 状 | Lyophilized |
| 纯 度 | >90% as determined by SDS-PAGE. |
| 缓 冲 液 | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| 保存条件 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
The membrane-bound adenylyl cyclases (ACs) represent one of the major families of effector enzymes for G protein-coupled receptors. Eight human AC isoforms (AC1 through AC4), encoded by separate genes, have been identified up to now. Most of the adenylate cyclase genes are comprised of 11-26 exons and distributed over a q6-430 kb. The majority of the adenylate cyclases previously described are expressed discretely in defined peripheral tissues, the type 4 adenylate cyclase (AC4) is apparently expressed in a variety of peripheral tissues and in the central nervous system, mainly in olfactory system. AC5 proteins are localized on photoreceptor cells and are also designated as GC1 and GC2. The AC5 protein resembles the other adenylyl cyclases in its predicted and proposed structure. AC5 resembles the type 6 (AC6) adenylyl cyclase in its amino acid sequence but becomes divergent at N and C-terminal ends. The AC5 and AC6 proteins are co-localized in most of the visual organs (photoreceptor cells) and are associated with other protein complexes. Both AC5 and AC6 enzymes play an important role in synaptic plasticity by coordinating overlapping synaptic inputs from Gs and Gi coupled receptor stimulation. SWISS: O43306 Gene ID: 112 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |