| 产品编号 | bs-104339P |
| 英文名称 | Recombinant Human PADI4 Protein, N-GST & C-His |
| 中文名称 | |
| 别 名 | Protein-arginine deiminase type-4; 3.5.3.15; HL-60 PAD; Peptidylarginine deiminase IV; Protein-arginine deiminase type IV; PADI4; PAD4; PADI5; PDI5 |
| 克 隆 号 | |
| 理论分子量 | 102.13 kDa |
| 性 状 | Lyophilized |
| 纯 度 | >90% as determined by SDS-PAGE. |
| 缓 冲 液 | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| 保存条件 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
PADI4 (peptidyl arginine deiminase, type IV) catalyzes the deimination of arginine residues of proteins. Down-regulates histone H3 and H4 arginine methylation, both by preventing arginine methylation by CARM1 and HRMT1L2/PRMT1 and by converting methylarginine to citrulline. subcellular location at cytoplasmic granules. Belongs to the protein arginine deiminase family. This gene may play a role in granulocyte and macrophage development leading to inflammation and immune response. SWISS: Q9UM07 Gene ID: 23569 PADI4或称PAD4 (Protein-arginine deiminase type IV) 是关节炎相关基因，分子量为：74kDa。有学者认为：PADI4也称Ⅳ型肽基精氨酸脱氨酶，该蛋白与关节炎的发生关系密切。PADI4 基因能够合成一种酶，将精氨酸变为桔霉素，当含桔霉素蛋白质的数量超过正常标准后，人体血液中便会出现攻击含桔霉素的蛋白质的抗体，这种机理是导致关节炎的重要因素之一。 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
