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Recombinant Human TGFBR2/TGFR-2 Protein, N-His (bs-104337P)  
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20ug/980.00元
50ug/1880.00元
100ug/2680.00元
大包装/询价
产品编号 bs-104337P
英文名称 Recombinant Human TGFBR2/TGFR-2 Protein, N-His
中文名称
别    名 TGF-beta receptor type-2; TGFR-2; 2.7.11.30; TGF-beta type II receptor; Transforming growth factor-beta receptor type II; TGF-beta receptor type II; TbetaR-II; TGFBR2  
克 隆 号
理论分子量 16.13 kDa
性    状 Lyophilized
纯    度 >90% as determined by SDS-PAGE.
缓 冲 液 Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
保存条件 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized.

SWISS:
P37173

Gene ID:
7048

细胞膜受体(Membrane Receptors) TGFβR2及家族在进化过程中结构和功能高度保守。参与细胞因子信号传导,调节多种细胞的生长、分化,在胚胎发育、组织器官形态发生、细胞的分化、增值及免疫调节等方面都起着重要作用。此抗体主要用于散发性胃癌、结肠癌及T细胞淋巴瘤和头颈部肿瘤方面的研究。
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