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Recombinant Human ANTXR1 Protein, C-His (bs-104309P)  
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20ug/1280.00元
50ug/2580.00元
100ug/4180.00元
大包装/询价
产品编号 bs-104309P
英文名称 Recombinant Human ANTXR1 Protein, C-His
中文名称
别    名 Anthrax toxin receptor 1; Tumor endothelial marker 8; ANTXR1; ATR; TEM8  
克 隆 号
理论分子量 24.46 kDa
性    状 Lyophilized
纯    度 >90% as determined by SDS-PAGE.
缓 冲 液 Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
保存条件 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq, Oct 2008]

SWISS:
Q9H6X2

Gene ID:
84168

肿瘤血管内皮标志物8是I型跨膜蛋白,是一种肿瘤特异性血管内皮标记蛋白。
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