| 产品编号 | bs-104282P |
| 英文名称 | Recombinant Human CD169/SIGLEC1 Protein, C-Fc |
| 中文名称 | |
| 别 名 | Sialoadhesin; Sialic acid-binding Ig-like lectin 1; Siglec-1; CD169; SIGLEC1; SN |
| 克 隆 号 | |
| 理论分子量 | 201.59 kDa |
| 性 状 | Lyophilized |
| 纯 度 | >90% as determined by SDS-PAGE. |
| 缓 冲 液 | Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| 保存条件 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a lectin-like adhesion molecule that binds glycoconjugate ligands on cell surfaces in a sialic acid-dependent manner. It is a type I transmembrane protein expressed only by a subpopulation of macrophages and is involved in mediating cell-cell interactions. Alternative splicing produces a transcript variant encoding an isoform that is soluble rather than membrane-bound; however, the full-length nature of this variant has not been determined. [provided by RefSeq, Jul 2008]. SWISS: Q9BZZ2 Gene ID: 6614 CD169，又称sialoadhesin（Sn）或Siglee-1，这是一种200kDa的I型跨膜糖蛋白，由炎性巨噬细胞特异性表达，在细胞-细胞或细胞-基质的相互作用中发挥主要作用。可识别乳癌细胞的MUC1（CD227）和T细胞的CD43。CD169在脾、淋巴结、骨髓的基质巨噬细胞上表达最强，在肝、肠、肺的长驻巨噬细胞上中等表达，慢性炎组织的巨噬细胞，例如类风湿性滑膜、动脉粥样硬化性斑块，也强烈表达CD169。 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
