| 产品编号 | bs-104211P |
| 英文名称 | Recombinant Human ELP3 Protein, N-His |
| 中文名称 | |
| 别 名 | Elongator complex protein 3; tRNA uridine(34) acetyltransferase; Protein lysine acetyltransferase ELP3; hELP3; ELP3 |
| 克 隆 号 | |
| 理论分子量 | 55.86 kDa |
| 性 状 | Lyophilized |
| 纯 度 | >90% as determined by SDS-PAGE. |
| 缓 冲 液 | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| 保存条件 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
ELP3 is the catalytic subunit of the histone acetyltransferase elongator complex, which contributes to transcript elongation and also regulates the maturation of projection neurons (Creppe et al., 2009 [PubMed 19185337]).[supplied by OMIM, Apr 2009] SWISS: Q9H9T3 Gene ID: 55140 RNA聚合酶II延伸复合体的催化tRNA乙酰转移酶亚基，是RNA聚合酶II（Pol II）全酶的组成部分，参与转录伸长。多个tRNA修饰需要拉伸配合物，包括mcm5U（5-甲氧基羰基甲基尿苷）、mcm5s2U（5-甲氧基羰基甲基-2-硫脲定）和ncm5U（5-氨基甲酰甲基尿苷）。在拉长复合物中，通过调节tRNAs中34位的摆动碱基中羧甲基尿苷的形成，充当tRNA尿苷（34）乙酰转移酶。也可以通过介导目标蛋白质的乙酰化而作为蛋白质赖氨酸乙酰转移酶。然而，这种活性在体内尚不清楚，最近的证据表明ELP3主要作为 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
