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产品中心-北京博奥森生物技术有限公司
Recombinant Human LITAF/PIG7/SIMPLE Protein, N-GST & C-His (bs-104205P)  
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20ug/980.00元
50ug/1880.00元
100ug/2680.00元
大包装/询价
产品编号 bs-104205P
英文名称 Recombinant Human LITAF/PIG7/SIMPLE Protein, N-GST & C-His
中文名称
别    名 Small integral membrane protein of lysosome/late endosome; LITAF; SIMPLE; p53-induced gene 7 protein; LPS-induced TNF-alpha factor; Lipopolysaccharide-induced tumor necrosis factor-alpha factor; PIG7  
克 隆 号
理论分子量 35.8 kDa
性    状 Lyophilized
纯    度 >90% as determined by SDS-PAGE.
缓 冲 液 Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
保存条件 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppresor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2008]

SWISS:
Q99732

Gene ID:
9516

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