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产品中心-北京博奥森生物技术有限公司
Recombinant Human LRSAM1/hTAL Protein, N-His (bs-104204P)  
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20ug/980.00元
50ug/1880.00元
100ug/2680.00元
大包装/询价
产品编号 bs-104204P
英文名称 Recombinant Human LRSAM1/hTAL Protein, N-His
中文名称
别    名 hTAL; RING-type E3 ubiquitin transferase LRSAM1; Leucine-rich repeat and sterile alpha motif-containing protein 1; TAL; E3 ubiquitin-protein ligase LRSAM1; LRSAM1; Tsg101-associated ligase  
克 隆 号
理论分子量 22.1 kDa
性    状 Lyophilized
纯    度 >90% as determined by SDS-PAGE.
缓 冲 液 Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
保存条件 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 LRSAM1 is an E3 ubiquitin-protein ligase that mediates monoubiquitination of TSG101 at multiple sites, leading to inactivation of the ability of TSG101 to sort endocytic (EGF receptors) and exocytic (HIV-1 viral proteins) cargos. It selectively regulates cell adhesion molecules and plays a role in receptor endocytosis and viral budding. LRSAM1 contains a RING-type zinc finger, 5 leucine-rich repeats and 1 SAM (sterile alpha motif) domain. The coiled coil domains interact with the SB domain of TSG101. The PTAP motifs mediate the binding to UEV domains. There are 3 isoforms produced by alternative splicing.

SWISS:
Q6UWE0

Gene ID:
90678

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