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产品中心-北京博奥森生物技术有限公司
Recombinant Human CYP2E1 Protein, N-His (bs-104189P)  
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20ug/980.00元
50ug/1880.00元
100ug/2680.00元
大包装/询价
产品编号 bs-104189P
英文名称 Recombinant Human CYP2E1 Protein, N-His
中文名称
别    名 CYP2E; 4-nitrophenol 2-hydroxylase; CYP2E1; Cytochrome P450 2E1; CYPIIE1; Cytochrome P450-J  
克 隆 号
理论分子量 55.67 kDa
性    状 Lyophilized
纯    度 >90% as determined by SDS-PAGE.
缓 冲 液 Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
保存条件 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and biosynthesis. Cytochrome P450 2E1 is induced by ethanol, diabetes and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, and exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer.

SWISS:
P05181

Gene ID:
1571

细胞色素P450 2E1(CYP2E1)可被乙醇等化合物诱导, 参与多种前致癌物(N-亚硝胺、苯胺、氯乙烯、氨基甲酸乙酯)的代谢活化,诱发肿瘤的发生。
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