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产品中心-北京博奥森生物技术有限公司
Recombinant Human ITIH4 Protein, N-His (bs-104105P)  
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20ug/980.00元
50ug/1880.00元
100ug/2680.00元
大包装/询价
产品编号 bs-104105P
英文名称 Recombinant Human ITIH4 Protein, N-His
中文名称
别    名 Inter-alpha-trypsin inhibitor family heavy chain-related protein; Inter-alpha-trypsin inhibitor heavy chain H4; PK120; PK-120; Plasma kallikrein sensitive glycoprotein 120; Inter-alpha-inhibitor heavy chain 4; ITIHL1; ITIH4; IHRP; ITI-HC4; ITI heavy chain H4; Gp120  
克 隆 号
理论分子量 28.86 kDa
性    状 Lyophilized
纯    度 >90% as determined by SDS-PAGE.
缓 冲 液 Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
保存条件 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 The inter-alpha-trypsin inhibitor (ITI) family is a group of structurally related plasma serine protease inhibitors synthesized in the liver and built up from different combinations of three highly homologous heavy chains (ITI-HI, ITI-H2 and ITI-H3) and one light chain (Bikunin). Another member of the ITI family, ITI-H4, harbors a proline-rich region (PRR) in its C-terminus. ITI is a glycoprotein composed of three polypeptides linked by chondroitin sulphate: two heavy chains, ITI-H1 and ITI-H2, and Bikunin. Bikunin confers the protease-inhibitor function of ITI. The heavy chains of the ITI family, designated as SHAPs (for serum-derived hyaluronan-associated proteins), bind covalently to hyaluronic acid (HA), resulting in pericellular matrix stabilization. While the ITI family is primarily composed of multi-polypeptide molecules, ITI-H4 is a single chain molecule. Unlike other ITI family members, the gene transcriptions and products for rat and human ITI-H4 demonstrate marked differences, suggesting possible species-specific functions for ITI-H4. The gene encoding human ITI-H4 maps to chromosome 3p21.1.

SWISS:
Q14624

Gene ID:
3700

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