| 产品编号 | bs-104102P |
| 英文名称 | Recombinant Human CD59 Protein, N-His-SUMO |
| 中文名称 | |
| 别 名 | MSK21; MAC-inhibitory protein; MEM43 antigen; MAC-IP; MIN2; MIRL; HRF20; Protectin; 1F5 antigen; MIC11; MIN3; Membrane inhibitor of reactive lysis; MACIF; 20 kDa homologous restriction factor; CD59; MIN1; CD59 glycoprotein; HRF-20; Membrane attack complex inhibition factor |
| 克 隆 号 | |
| 理论分子量 | 23.98 kDa |
| 性 状 | Lyophilized |
| 纯 度 | >90% as determined by SDS-PAGE. |
| 缓 冲 液 | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| 保存条件 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008] SWISS: P13987 Gene ID: 966 反应性溶血膜抑制蛋白（CD59）是血细胞膜上糖化磷脂酰肌醇（GPI）锚定蛋白，具有抑制补体系统激活，参与信号传递，有协助T淋巴细胞活化功能,CD59在补体调节过程中起着很主要的作用。 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
