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产品中心-北京博奥森生物技术有限公司
Recombinant Human APBB1IP Protein, N-His (bs-104086P)  
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20ug/980.00元
50ug/1880.00元
100ug/2680.00元
大包装/询价
产品编号 bs-104086P
英文名称 Recombinant Human APBB1IP Protein, N-His
中文名称
别    名 Proline-rich protein 73; RIAM; RARP-1; APBB1-interacting protein 1; Rap1-GTP-interacting adapter molecule; PREL-1; Proline-rich EVH1 ligand 1; Amyloid beta A4 precursor protein-binding family B member 1-interacting protein; PREL1; RARP1; APBB1IP; Retinoic acid-responsive proline-rich protein 1  
克 隆 号
理论分子量 31.33 kDa
性    状 Lyophilized
纯    度 >90% as determined by SDS-PAGE.
缓 冲 液 Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
保存条件 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 APBB1IP is a 666 amino acid protein that contains one PH domain, one Ras-associating domain and belongs to the MRL family. Encoded by a gene that maps to human chromosome 10p12.1, APBB1IP likely functions in signal transduction from Ras activation to Actin cytoskeletal remodeling. APBB1IP also suppresses insulin-induced promoter activities, by way of SRE and AP1. The two proline-rich regions of APBB1IP are necessary for AP1 transcription suppression. Ubiquitously expressed, with high expression in thymus, spleen, lymph node, bone marrow and peripheral leukocytes, APBB1IP is induced by all-trans-retinoic acid (ATRA) and mediates Rap 1-induced adhesion. APBB1IP also interacts with RAP 1A, Profilin-1, VASP and Mena.

SWISS:
Q7Z5R6

Gene ID:
54518

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