| 产品编号 | bs-104051P |
| 英文名称 | Recombinant Human KRT4 Protein, N-His |
| 中文名称 | |
| 别 名 | CYK4; Keratin-4; Type-II keratin Kb4; Cytokeratin-4; KRT4; K4; Keratin; type II cytoskeletal 4; CK-4 |
| 克 隆 号 | |
| 理论分子量 | 39.95 kDa |
| 性 状 | Lyophilized |
| 纯 度 | >90% as determined by SDS-PAGE. |
| 缓 冲 液 | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| 保存条件 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in differentiated layers of the mucosal and esophageal epithelia with family member KRT13. Mutations in these genes have been associated with White Sponge Nevus, characterized by oral, esophageal, and anal leukoplakia. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008] SWISS: P19013 Gene ID: 3851 结构蛋白（Structural Proteins） 细胞角蛋白是一类与结构相关的蛋白家族，他们在上皮细胞中形成了细胞骨架中间丝。角蛋白在上皮细胞中往往成对存在，具有组织和细胞特异性。存在于口腔黏膜、鼻腔、食道和肛门生殖器上皮中的特异角蛋白为CK4和CK13。CK4是II型角蛋白，普遍存在于非角质化的鳞状上皮细胞中，CK4表达于基底细胞，也表达于鳞状细胞癌。 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
