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产品中心-北京博奥森生物技术有限公司
Recombinant Human TMOD4 Protein, N-His (bs-104038P)  
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20ug/980.00元
50ug/1880.00元
100ug/2680.00元
大包装/询价
产品编号 bs-104038P
英文名称 Recombinant Human TMOD4 Protein, N-His
中文名称
别    名 TMOD4; Skeletal muscle tropomodulin; Sk-Tmod; Tropomodulin-4  
克 隆 号
理论分子量 21.06 kDa
性    状 Lyophilized
纯    度 >90% as determined by SDS-PAGE.
缓 冲 液 Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
保存条件 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Originally isolated from human erythrocytes, the tropomodulin (TMOD) family of proteins cap the pointed end of actin filaments (1,2). A component of the membrane skeleton, TMOD binds to the amino terminus of tropomyosin, which coats the surface of actin, and thus blocks the elongation and depolymerization of actin filaments (3,4). Four TMOD isoforms, TMOD1 - TMOD4, have been characterized in humans (2). TMOD expression is isoform-specific; TMOD3 is expressed ubiquitously, whereas TMOD2 and TMOD4 are expressed in neuronal tissue and muscle, respectively (5). TMOD4, which has a similar organization to TMOD2, is intergenically spliced by the putative transformation suppressor gene product YL-1 (1). The human TMOD4 gene maps to the telomeric end of chromosome 1q12, and encodes a 351 amino acid protein (1,5). The expression and chromosomal location of the TMOD4 gene make it a candidate for limb girdle musclular dystrophy 1B (5).

SWISS:
Q9NZQ9

Gene ID:
29765

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