| 产品编号 | bs-103992P |
| 英文名称 | Recombinant Human ARPC1B Protein, N-His |
| 中文名称 | |
| 别 名 | Actin-related protein 2/3 complex subunit 1B; p41-ARC; Arp2/3 complex 41 kDa subunit; ARC41; ARPC1B |
| 克 隆 号 | |
| 理论分子量 | 43.11 kDa |
| 性 状 | Lyophilized |
| 纯 度 | >90% as determined by SDS-PAGE. |
| 缓 冲 液 | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| 保存条件 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1A. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages. This protein also has a role in centrosomal homeostasis by being an activator and substrate of the Aurora A kinase. [provided by RefSeq, Mar 2011] SWISS: O15143 Gene ID: 10095 Arp2/3复合物的组分，一种多蛋白复合物，在成核促进因子（NPF）刺激下介导肌动蛋白聚合。Arp2/3复合物介导细胞质中分支肌动蛋白网络的形成，为细胞运动提供动力。除了在细胞质骨架中的作用外，Arp2/3复合物还促进细胞核中肌动蛋白的聚合，从而调节基因转录和受损DNA的修复。Arp2/3复合物通过促进核肌动蛋白聚合促进同源重组（HR）修复，从而导致双链断裂（dsb）的运动。 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
