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产品中心-北京博奥森生物技术有限公司
Recombinant Human KAT7 Protein, N-His (bs-103972P)  
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20ug/980.00元
50ug/1880.00元
100ug/2680.00元
大包装/询价
产品编号 bs-103972P
英文名称 Recombinant Human KAT7 Protein, N-His
中文名称
别    名 KAT7; HBOa; HBO1; MYST-2; MYST2; Lysine acetyltransferase 7; MOZ; YBF2/SAS3; SAS2 and TIP60 protein 2; Histone acetyltransferase binding to ORC1; Histone acetyltransferase KAT7  
克 隆 号
理论分子量 35.06 kDa
性    状 Lyophilized
纯    度 >90% as determined by SDS-PAGE.
缓 冲 液 Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
保存条件 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 In the cell, transcription is regulated in part by the histone modification of chromatin. Specifically, histone acetyltransferase proteins and their associated complexes function with co-activators to regulate transcription. One family of histone acetyltransferases is the MYST family of transcriptional silencers, which is linked to ORC (origin recognition complex) function. The ORC is an initiator protein for DNA replication and mediates the acetylation of chromatin to control both DNA replication and gene expression. HBO1 (histone acetyltransferase binding to ORC) is a MYST family protein that interacts with ORC1, the largest subunit of the human ORC complex. HBO1 is a nuclear protein that is highly expressed in human testis. In addition to binding ORC, HBO1 represses AR (androgen receptor)-mediated transcription by binding AR through its N-terminal transcriptional repression domain. HBO1 may play a role in regulating AR-dependent gene transcription in normal and prostate cancer cells.

SWISS:
O95251

Gene ID:
11143

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