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产品中心-北京博奥森生物技术有限公司
Recombinant Human PICK1 Protein, N-His-SUMO & C-Strep (bs-103953P)  
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20ug/980.00元
50ug/1880.00元
100ug/2680.00元
大包装/询价
产品编号 bs-103953P
英文名称 Recombinant Human PICK1 Protein, N-His-SUMO & C-Strep
中文名称
别    名 PRKCA-binding protein; Protein interacting with C kinase 1; PRKCABP; Protein kinase C-alpha-binding protein; PICK1  
克 隆 号
理论分子量 23.98 kDa
性    状 Lyophilized
纯    度 >90% as determined by SDS-PAGE.
缓 冲 液 Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
保存条件 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate heteromeric ACCN3/ACCN2 channel.

SWISS:
Q9NRD5

Gene ID:
9463

PICK1是衔接PKCα和膜上众多受体的关键蛋白之一,是细胞质中的膜结合蛋白,在蛋白质转运,以及细胞内信号转导过程中发挥重要作用;而在男性不育方面,PICK1蛋白也是促进精子顶体发育的关键蛋白,缺失PICK1蛋白将导致精子受破坏,失去活动能力和受精能力。
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