| 产品编号 | bs-103870P |
| 英文名称 | Recombinant Human PLEKHO1 Protein, N-His |
| 中文名称 | |
| 别 名 | PH domain-containing family O member 1; CK2-interacting protein 1; Osteoclast maturation-associated gene 120 protein; OC120; JBP; Casein kinase 2-interacting protein 1; C-Jun-binding protein; CKIP1; PLEKHO1; CKIP-1; Pleckstrin homology domain-containing family O member 1 |
| 克 隆 号 | |
| 理论分子量 | 16.4 kDa |
| 性 状 | Lyophilized |
| 纯 度 | >90% as determined by SDS-PAGE. |
| 缓 冲 液 | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| 保存条件 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
Plays a role in the regulation of the actin cytoskeleton through its interactions with actin capping protein (CP). May function to target CK2 to the plasma membrane thereby serving as an adapter to facilitate the phosphorylation of CP by protein kinase 2(CK2). Appears to target ATM to the plasma membrane. Appears to also inhibit tumor cell growth by inhibiting AKT-mediated cell-survival. Also implicated in PI3K-regulated muscle differentiation, the regulation of AP-1 activity (plasma membrane bound AP-1 regulator that translocates to the nucleus) and the promotion of apoptosis induced by tumor necrosis factor TNF. When bound to PKB, it inhibits it probably by decreasing PKB level of phosphorylation. SWISS: Q53GL0 Gene ID: 51177 酪蛋白激酶2相互作用蛋白1是近年来发现的一种重要分子，它通过与其他分子的相互作用在许多细胞行为中都发挥着重要的作用。 CKIP-1还具有促进细胞凋亡的作用。CKIP-1可以与caspase-3形成正反馈环，增强肿瘤细胞的凋亡。 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
