| 产品编号 | bs-103853P |
| 英文名称 | Recombinant Human BIRC7 Protein, N-His-SUMO |
| 中文名称 | |
| 别 名 | BIRC7; p30-Livin; Melanoma inhibitor of apoptosis protein; LIVIN; Baculoviral IAP repeat-containing protein 7; Kidney inhibitor of apoptosis protein; Truncated livin; RNF50; KIAP; Livin; RING-type E3 ubiquitin transferase BIRC7; RING finger protein 50; tLivin; MLIAP; ML-IAP |
| 克 隆 号 | |
| 理论分子量 | 22.83 kDa |
| 性 状 | Lyophilized |
| 纯 度 | >90% as determined by SDS-PAGE. |
| 缓 冲 液 | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| 保存条件 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
Livin is a novel member of the IAP protein family and contains a single baculoviral IAP repeat (BIR) domain and a RING finger domain and has two isoforms termed Livin alpha and Livin beta. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. The two isoforms of Livin appear to have different functions and tissue distributions. SWISS: Q96CA5 Gene ID: 79444 Livin—属于凋亡蛋白抑制因子家族（inhibitor of apoptosis proteins，IAP） Livin是凋亡抑制蛋白家族的新成员，主要通过抑制Caspases蛋白发挥抑制细胞凋亡的作用,主要在胎盘组织中表达，同时在一些肿瘤组织中呈高表达，尤其是在黑色素瘤细胞系表达水平最高。 经研究表明，Livin与肿瘤的发生、发展关系密切,是一个有潜在价值的肿瘤标志物，此外，反义Livin以及Livin活性抑制物的研究有望成为肿瘤治疗的新靶点。 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
