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产品中心-北京博奥森生物技术有限公司
Recombinant Human GNAQ Protein, N-His (bs-103667P)  
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20ug/980.00元
50ug/1880.00元
100ug/2680.00元
大包装/询价
产品编号 bs-103667P
英文名称 Recombinant Human GNAQ Protein, N-His
中文名称
别    名 GNAQ; GAQ; Guanine nucleotide-binding protein G(q) subunit alpha; Guanine nucleotide-binding protein alpha-q  
克 隆 号
理论分子量 44.3 kDa
性    状 Lyophilized
纯    度 >90% as determined by SDS-PAGE.
缓 冲 液 Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
保存条件 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 GNAQ belong to the family of heterotrimeric Guanine nucleotide-binding proteins proteins that couple cell surface, 7-transmembrane domain receptors to intracellular signaling pathways. Receptor activation catalyzes the exchange of GTP for GDP bound to the inactive G protein alpha subunit resulting in a conformational change and dissociation of the complex. GNAQ is the alpha subunit of one of the heterotrimeric GTP-binding proteins that mediates stimulation of phospholipase C-beta. in recent studies over expression of GNAQ is associated with cardiomyocyte apoptosis.

SWISS:
P50148

Gene ID:
2776

Gαq是G蛋白家族成员之一,是Gq蛋白的功能单位。其功能为传导来自GPCR的信号到细胞内。研究证明,Gαq与免疫细胞活化、增殖、死亡、分化、迁移,细胞因子分泌以及自身免疫等均有非常密切的关系。
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