| 产品编号 | bs-103630P |
| 英文名称 | Recombinant Human GIPC1 Protein, N-His |
| 中文名称 | |
| 别 名 | GIPC; RGS19-interacting protein 1; Tax interaction protein 2; TIP-2; Synectin; RGS-GAIP-interacting protein; C19orf3; PDZ domain-containing protein GIPC1; RGS19IP1; GIPC1; GAIP C-terminus-interacting protein |
| 克 隆 号 | |
| 理论分子量 | 32.53 kDa |
| 性 状 | Lyophilized |
| 纯 度 | >90% as determined by SDS-PAGE. |
| 缓 冲 液 | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| 保存条件 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
GIPC, for GAIP interacting protein at the C terminus (also designated SEMCAP-1 or synectin), is a PDZ domain containing protein that interacts with RGS-GAIP, a GTPase-activating protein (GAP) for G(a i) subunits. GIPC was also identified as TIP-2, a protein that interacts with the viral oncoprotein TAX, which transactivates viral and cellular promoters through interactions with various transcription factors. PDZ domain-containing proteins are primarily localized to cell-cell junctions in epithelial cells and neurons where they coordinate the assembly of multiprotein complexes. GIPC specifically localizes to clusters of vesicles near the plasma membrane and participates in G protein-coupled signaling pathway involved in regulating clathrin-coated vesicular trafficking. GIPC also associates with membrane bound semaphorin F (M-SemF), which is involved in neuronal axon growth, and it appears to regulate the subcellular distribution of M-SemF in the brain. SWISS: O14908 Gene ID: 10755 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
