| 产品编号 | bs-103594P |
| 英文名称 | Recombinant Human NME1 Protein, N-His |
| 中文名称 | |
| 别 名 | NDPKA; NME1; NDP kinase A; Nucleoside diphosphate kinase A; Granzyme A-activated DNase; NM23; Metastasis inhibition factor nm23; GAAD; Tumor metastatic process-associated protein; NDK A; NM23-H1 |
| 克 隆 号 | |
| 理论分子量 | 19.31 kDa |
| 性 状 | Lyophilized |
| 纯 度 | >90% as determined by SDS-PAGE. |
| 缓 冲 液 | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| 保存条件 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. SWISS: P15531 Gene ID: 4830 nm23是一种转移抑制基因，主要用于胃肠道癌、乳腺癌、肺癌的多种恶性肿瘤的研究。大多数研究结果表明，nm23阳性表达与肿瘤转移负相关，与病人的预后呈正相关，但也有人研究报道与转移或预后无相关性，说明其结论仍有争议。 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
