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产品中心-北京博奥森生物技术有限公司
Recombinant Human PHGDH Protein, N-His (bs-103421P)  
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20ug/980.00元
50ug/1880.00元
100ug/2680.00元
大包装/询价
产品编号 bs-103421P
英文名称 Recombinant Human PHGDH Protein, N-His
中文名称
别    名 2-oxoglutarate reductase; Malate dehydrogenase; 3-PGDH; PGDH3; PHGDH; D-3-phosphoglycerate dehydrogenase  
克 隆 号
理论分子量 58.94 kDa
性    状 Lyophilized
纯    度 >90% as determined by SDS-PAGE.
缓 冲 液 Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
保存条件 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 This gene encodes the enzyme which is involved in the early steps of L-serine synthesis in animal cells. L-serine is required for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been found in a family with congenital microcephaly, psychomotor retardation and other symptoms. Multiple alternatively spliced transcript variants have been found, however the full-length nature of most are not known. [provided by RefSeq, Aug 2011]

SWISS:
O43175

Gene ID:
26227

催化3-磷酸-D-甘油酯可逆氧化为3-磷酸丙酮酸,这是L-丝氨酸磷酸化生物合成途径的第一步。还催化2-羟基戊二酸可逆氧化为2-酮戊二酸和(S)-苹果酸可逆氧化为草酰乙酸。
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