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产品中心-北京博奥森生物技术有限公司
Recombinant Human PPARGC1A Protein, N-His (bs-103338P)  
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20ug/980.00元
50ug/1880.00元
100ug/2680.00元
大包装/询价
产品编号 bs-103338P
英文名称 Recombinant Human PPARGC1A Protein, N-His
中文名称
别    名 LEM6; PGC1A; PPARGC1; Ligand effect modulator 6; PGC-1-alpha; PPAR-gamma coactivator 1-alpha; Peroxisome proliferator-activated receptor gamma coactivator 1-alpha; PPARGC-1-alpha; PPARGC1A; PGC1  
克 隆 号
理论分子量 22.11 kDa
性    状 Lyophilized
纯    度 >90% as determined by SDS-PAGE.
缓 冲 液 Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
保存条件 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity (referenced from entrez gene.

SWISS:
Q9UBK2

Gene ID:
10891

PGC-1α是一个新发现的转录激活因子,起到高游离脂肪酸刺激胰岛α细胞分泌的重要调控作用。
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