| 产品编号 | bs-103324P |
| 英文名称 | Recombinant Human ROCK1 Protein, N-His |
| 中文名称 | |
| 别 名 | Renal carcinoma antigen NY-REN-35; p160 ROCK-1; p160ROCK; Rho-associated protein kinase 1; Rho-associated; coiled-coil-containing protein kinase I; Rho-associated; coiled-coil-containing protein kinase 1; ROCK-I; ROCK1 |
| 克 隆 号 | |
| 理论分子量 | 42.9 kDa |
| 性 状 | Lyophilized |
| 纯 度 | >90% as determined by SDS-PAGE. |
| 缓 冲 液 | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| 保存条件 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. [provided by RefSeq]. SWISS: Q13464 Gene ID: 6093 ROCK1也是丝/苏氨基酸激酶的一种，可调节细胞因子，促进平滑肌收缩和肌动蛋白的形成,因此又称：含有卷曲螺旋的蛋白激酶。目前主要用于肿瘤浸润、转移方面的研究。 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
