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Recombinant Human CD123/IL3RA Protein, N-His (bs-103272P)  
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20ug/980.00元
50ug/1880.00元
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大包装/询价
产品编号 bs-103272P
英文名称 Recombinant Human CD123/IL3RA Protein, N-His
中文名称
别    名 IL-3R subunit alpha; IL-3 receptor subunit alpha; CD123; Interleukin-3 receptor subunit alpha; IL3R; IL-3R-alpha; IL3RA; IL-3RA  
克 隆 号
理论分子量 18.06 kDa
性    状 Lyophilized
纯    度 >90% as determined by SDS-PAGE.
缓 冲 液 Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
保存条件 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq, Jun 2012]

SWISS:
P26951

Gene ID:
3563

白细胞介素3受体α(IL-3Rα)又称CD123,是造血生长因子受体家族成员,CD123是未分化白血病干细胞的特异标志.在细胞信号转导、细胞凋亡及血液肿瘤发生中起重要作用.
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