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Recombinant Human CD112/Nectin-2/PVRL2 Protein, C-His (bs-103217P)  
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20ug/1280.00元
50ug/2580.00元
100ug/4180.00元
大包装/询价
产品编号 bs-103217P
英文名称 Recombinant Human CD112/Nectin-2/PVRL2 Protein, C-His
中文名称
别    名 Herpesvirus entry mediator B; Herpes virus entry mediator B; Nectin cell adhesion molecule 2; HVEB; PVRL2; Poliovirus receptor-related protein 2; CD112; PRR2; Nectin-2; HveB; NECTIN2  
克 隆 号
理论分子量 39.79 kDa
性    状 Lyophilized
纯    度 >90% as determined by SDS-PAGE.
缓 冲 液 Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
保存条件 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Nectin 2 is a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Can form trans-heterodimers with PVRL3/nectin-3.

SWISS:
Q92692

Gene ID:
5819

细胞粘附分子Nectin-2(CD112)是一种同源性非钙依赖型的CAM,属免疫球蛋白超家族,由nectin-1、nectin-2、nectin-3组成,广泛存在于肿瘤、正常细胞,神经细胞、内皮细胞等,CD112也是单纯疱疹病毒(HSV-1和HSV-2)的受体,具有同型或异型细胞粘附活性.在多发性硬化中呈现高表达。
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