| 产品编号 | bs-103187P |
| 英文名称 | Recombinant Human CD167a/DDR1 Protein, C-His |
| 中文名称 | |
| 别 名 | Protein-tyrosine kinase RTK-6; Protein-tyrosine kinase 3A; NTRK4; EDDR1; CAK; Tyrosine kinase DDR; Mammary carcinoma kinase 10; TRKE; Epithelial discoidin domain-containing receptor 1; CD167a; TRK E; Epithelial discoidin domain receptor 1; HGK2; CD167 antigen-like family member A; NEP; MCK-10; Tyrosine-protein kinase CAK; PTK3A; DDR1; Discoidin receptor tyrosine kinase; RTK6; Cell adhesion kinase |
| 克 隆 号 | |
| 理论分子量 | 46.87 kDa |
| 性 状 | Lyophilized |
| 纯 度 | >90% as determined by SDS-PAGE. |
| 缓 冲 液 | Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| 保存条件 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene is a RTK that is widely expressed in normal and transformed epithelial cells and is activated by various types of collagen. This protein belongs to a subfamily of tyrosine kinase receptors with a homology region to the Dictyostelium discoideum protein discoidin I in their extracellular domain. Its autophosphorylation is achieved by all collagens so far tested (type I to type VI). In situ studies and Northern-blot analysis showed that expression of this encoded protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, this protein is significantly over-expressed in several human tumors from breast, ovarian, esophageal, and pediatric brain. This gene is located on chromosome 6p21.3 in proximity to several HLA class I genes. Alternative splicing of this gene results in multiple transcript variants. SWISS: Q08345 Gene ID: 780 DDR-1属酪氨酸激酶受体家族：用于肿瘤方面的研究 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
