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Recombinant Human EZH2 Protein, N-His (bs-103072P)  
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20ug/980.00元
50ug/1880.00元
100ug/2680.00元
大包装/询价
产品编号 bs-103072P
英文名称 Recombinant Human EZH2 Protein, N-His
中文名称
别    名 ENX-1; Enhancer of zeste homolog 2; EZH2; Lysine N-methyltransferase 6; KMT6; Histone-lysine N-methyltransferase EZH2  
克 隆 号
理论分子量 18.44 kDa
性    状 Lyophilized
纯    度 >90% as determined by SDS-PAGE.
缓 冲 液 Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
保存条件 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Feb 2011].

SWISS:
Q15910

Gene ID:
2146

    EZH2(enhancer of zeste homolog 2)是新识别的一种人类基因,是果蝇zeste基因增强子的人类同源基因,Polycomb group基因家族的重要成员之一。 EZH2在多种肿瘤中高表达,具有促进细胞增殖,肿瘤细胞的扩散的恶性表型,EZH2在肿瘤中的作用成为研究热门。EZHZ在前列腺癌、乳腺癌、膀胧癌、肝细胞癌、大肠癌、胃癌中高表达;局限性前列腺癌、乳腺癌、膀胧癌高表达EZH2,则临床预后较差。因此EZH2可作为肿瘤标志物监测肿瘤的
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