| 产品编号 | bs-103068P |
| 英文名称 | Recombinant Human CD191/CCR1 Protein, N-His |
| 中文名称 | |
| 别 名 | CMKR1; SCYAR1; Macrophage inflammatory protein 1-alpha receptor; CMKBR1; MIP-1alpha-R; HM145; CC-CKR-1; RANTES-R; LD78 receptor; CCR-1; C-C chemokine receptor type 1; CCR1; CD191; C-C CKR-1 |
| 克 隆 号 | |
| 理论分子量 | 13.26 kDa |
| 性 状 | Lyophilized |
| 纯 度 | >90% as determined by SDS-PAGE. |
| 缓 冲 液 | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| 保存条件 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
bs-1169P is a synthetic peptide derived from human CCR-1. This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p. [provided by RefSeq, Jul 2008] SWISS: P32246 Gene ID: 1230 趋化因子是当今细胞因子研究领域的热点之一,它参与多种免疫及炎症反应,在感染、肿瘤的生长与转移、组织修复及创伤愈合等病理生理过程中发挥重要作用. C-C型趋化因子受体1(CCR1)主要在嗜酸粒细胞，Th2淋巴细胞，肥大细胞，支气管上皮细胞上表达.CCR1在肿瘤的生长与转移方面起到一定的作用. |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
