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产品中心-北京博奥森生物技术有限公司
Recombinant Human VSIR/VISTA Protein, C-His (bs-103063P)  
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20ug/1280.00元
50ug/2580.00元
100ug/4180.00元
大包装/询价
产品编号 bs-103063P
英文名称 Recombinant Human VSIR/VISTA Protein, C-His
中文名称
别    名 V-set domain-containing immunoregulatory receptor; C10orf54; VSIR; VISTA; SISP1; Stress-induced secreted protein-1; Platelet receptor Gi24; V-set immunoregulatory receptor; Sisp-1; V-type immunoglobulin domain-containing suppressor of T-cell activation  
克 隆 号
理论分子量 22.35 kDa
性    状 Lyophilized
纯    度 >90% as determined by SDS-PAGE.
缓 冲 液 Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
保存条件 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Platelet receptor GI24, also known as SISP1 or PP2135, is a 311 amino acid single-pass type I membrane protein that contains one Ig-like (immunoglobulin-like) domain. GI24 is thought to contribute to tumor-invasive growth in the collagen matrix and is encoded by a gene that maps to human chromosome 10q22.1. Chromosome 10 contains over 800 genes, 135 million nucleotides and comprises nearly 4.5% of the human genome. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome. The chromosome 10 encoded gene ERCC6 is important for DNA repair and is linked to Cockayne syndrome which is characterized by extreme photosensitivity and premature aging. Tetrahydrobiopterin deficiency and a number of syndromes involving defective skull and facial bone fusion are also linked to chromosome 10. As with most trisomies, trisomy 10 is rare and is deleterious.

SWISS:
Q9H7M9

Gene ID:
64115

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