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产品中心-北京博奥森生物技术有限公司
Recombinant Human LAT2 Protein, N-His (bs-103001P)  
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20ug/980.00元
50ug/1880.00元
100ug/2680.00元
大包装/询价
产品编号 bs-103001P
英文名称 Recombinant Human LAT2 Protein, N-His
中文名称
别    名 NTAL; LAT2; Membrane-associated adapter molecule; WBS15; LAB; WBSCR15; Williams-Beuren syndrome chromosomal region 5 protein; WBSCR5; Non-T-cell activation linker; Linker for activation of T-cells family member 2; Linker for activation of B-cells; Williams-Beuren syndrome chromosomal region 15 protein  
克 隆 号
理论分子量 21.78 kDa
性    状 Lyophilized
纯    度 >90% as determined by SDS-PAGE.
缓 冲 液 Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
保存条件 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Non-T cell activation linker (NTAL), a transmembrane adaptor protein, is also designated membrane-associated adapter molecule, Williams-Beuren syndrome chromosome region 15 protein or LAB (linker of activated B cells). NTAL is present in membrane microdomains (rafts) of B cells, NK cells and myeloid cells, and in monocytes and mast cells, but not in resting T lymphocytes. NTAL becomes rapidly tyrosine-phosphorylated upon cross-linking of the B cell receptor (BCR) or of high-affinity Fc g and Fc e receptors of myeloid cells and then associates with the cytoplasmic signaling molecules. NTAL is highly expressed in spleen, lymph node germinal centers and peripheral blood lymphocytes. Defects in the gene encoding for NTAL may cause the musculo-skeletal and cardio-vascular abnormalities that characterize the rare developmental disorder Williams-Beuren syndrome (WBS).

SWISS:
Q9GZY6

Gene ID:
7462

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