| 产品编号 | bs-102950P |
| 英文名称 | Recombinant Human CD172a/SIRPA Protein, C-His |
| 中文名称 | |
| 别 名 | BIT; Signal-regulatory protein alpha-1; Brain Ig-like molecule with tyrosine-based activation motifs; MFR; SIRP; Sirp-alpha-1; Sirp-alpha-2; PTPNS1; SIRPA; SHP substrate 1; CD172 antigen-like family member A; Sirp-alpha-3; Inhibitory receptor SHPS-1; Signal-regulatory protein alpha-3; CD172a; Tyrosine-protein phosphatase non-receptor type substrate 1; MyD-1 antigen; Bit; SHPS-1; Macrophage fusion receptor; Signal-regulatory protein alpha-2; SHPS1; MYD1; p84 |
| 克 隆 号 | |
| 理论分子量 | 41.14 kDa |
| 性 状 | Lyophilized |
| 纯 度 | >90% as determined by SDS-PAGE. |
| 缓 冲 液 | Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| 保存条件 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
Protein tyrosine phosphatases (PTPases) SHP1 and SHP2 are critical regulators in the intracellular signaling pathways that result in cell responses such as mitosis, differentiation, migration, survival, transformation or death. SHP2 is a signal transducer for several receptor tyrosine kinases and cytokine receptors. A novel SHP2 associated glycoprotein was recently cloned from human, rat, mouse and cattle by several labs and was designated SIRPa (1),SHPS1 , MyD1, BIT and p84. SIRPa is a new gene family containing at least fifteen members. SIRPa is a substrate of many activated tyrosine kinases such as insulin receptor, EGFR, PDGFR and src, and a specific docking protein for SHP2. SIRPa has regulatory effects on cellular responses induced by serum, growth factors, insulin, oncogenes, growth hormones and cell adhesion and plays a general role in different physiological and pathological processes. SWISS: P78324 Gene ID: 140885 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
