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产品中心-北京博奥森生物技术有限公司
Recombinant Human BCL10 Protein, N-His (bs-102880P)  
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20ug/980.00元
50ug/1880.00元
100ug/2680.00元
大包装/询价
产品编号 bs-102880P
英文名称 Recombinant Human BCL10 Protein, N-His
中文名称
别    名 CED-3/ICH-1 prodomain homologous E10-like regulator; CLAP; B-cell CLL/lymphoma 10; BCL10; CARD-containing molecule enhancing NF-kappa-B; Cellular homolog of vCARMEN; cCARMEN; CIPER; Bcl-10; hCLAP; Cellular-E10; CARD-like apoptotic protein; c-E10; Mammalian CARD-containing adapter molecule E10; B-cell lymphoma/leukemia 10; mE10  
克 隆 号
理论分子量 28.56 kDa
性    状 Lyophilized
纯    度 >90% as determined by SDS-PAGE.
缓 冲 液 Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
保存条件 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. [provided by RefSeq, Jul 2008]

SWISS:
O95999

Gene ID:
8915

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