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产品中心-北京博奥森生物技术有限公司
Recombinant Human PTGES Protein, N-His (bs-102866P)  
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20ug/980.00元
50ug/1880.00元
100ug/2680.00元
大包装/询价
产品编号 bs-102866P
英文名称 Recombinant Human PTGES Protein, N-His
中文名称
别    名 PGES; PTGES; Prostaglandin E synthase; MPGES1; Microsomal prostaglandin E synthase 1; MGST1-L1; PIG12; p53-induced gene 12 protein; Glutathione transferase PTGES; MGST1L1; MPGES-1; Glutathione peroxidase PTGES; Microsomal glutathione S-transferase 1-like 1  
克 隆 号
理论分子量 19.41 kDa
性    状 Lyophilized
纯    度 >90% as determined by SDS-PAGE.
缓 冲 液 Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
保存条件 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Prostaglandin E synthase catalyses conversion of COX derived PGH2 to PGE2. It is a member of the MAPEG family. It may contribute to the pathogenesis of collagen induced arthritis and mediate acute pain during inflammatory responses. The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses.

SWISS:
O14684

Gene ID:
9536

PTGES由白介素-1β诱导产生,可能参与P53诱导的凋亡过程。
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