| 产品编号 | bs-102836P |
| 英文名称 | Recombinant Human NEUROG3 Protein, N-His |
| 中文名称 | |
| 别 名 | NGN-3; BHLHA7; Protein atonal homolog 5; NGN3; bHLHa7; Class A basic helix-loop-helix protein 7; Neurogenin-3; ATOH5; NEUROG3 |
| 克 隆 号 | |
| 理论分子量 | 15.26 kDa |
| 性 状 | Lyophilized |
| 纯 度 | >90% as determined by SDS-PAGE. |
| 缓 冲 液 | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| 保存条件 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
Neurogenin-3 (NEUROG3) is expressed in endocrine progenitor cells and is required for endocrine cell development in the pancreas and intestine (Wang et al., 2006 [PubMed 16855267]). It belongs to a family of basic helix-loop-helix transcription factors involved in the determination of neural precursor cells in the neuroectoderm. SWISS: Q9Y4Z2 Gene ID: 50674 神经生物学相关蛋白（Neurobiology） Ngn3属于bHLH家族蛋白，是胰腺发育过程中短暂表达的蛋白，可能是胰腺内分泌细胞系的定向因子，一般在成熟胰岛中不存在。 Ngn3的表达会导致胰腺内分泌细胞数的增加外分泌细胞数的减少。因而胰岛β细胞并不是完全靠干细胞分化产生，主要是通过已分化胰岛β细胞的分裂增殖。 但近年来，有学者认为：Ngn3虽在胰腺发育中短暂表达，但是否存在使胰岛干细胞或前体细胞自我更新的能力尚未明确定论。 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
