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产品中心-北京博奥森生物技术有限公司
Recombinant Human DTNBP1 Protein, N-His (bs-102806P)  
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20ug/980.00元
50ug/1880.00元
100ug/2680.00元
大包装/询价
产品编号 bs-102806P
英文名称 Recombinant Human DTNBP1 Protein, N-His
中文名称
别    名 Dysbindin-1; Dysbindin; BLOC1S8; BLOC-1 subunit 8; HPS7 protein; Dystrobrevin-binding protein 1; Hermansky-Pudlak syndrome 7 protein; DTNBP1; Biogenesis of lysosome-related organelles complex 1 subunit 8  
克 隆 号
理论分子量 30.56 kDa
性    状 Lyophilized
纯    度 >90% as determined by SDS-PAGE.
缓 冲 液 Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
保存条件 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Dysbindin may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome-related organelles complex 1 (BLOC1), and binds to alpha and beta dystrobrevins, which are components of the dystrophin associated protein complex (DPC). Mutations in Dysbindin gene are associated with Hermansky-Pudlak syndrome type 7. Dysbindin gene may also be associated with schizophrenia. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

SWISS:
Q96EV8

Gene ID:
84062

dysbindin-1(DTNBP1)基因是一种精神分裂症的易感基因, 该基因实际上也是影响一般智力和认知能力相关的关键因素。因此研究人员认为DTNBP1在大脑细胞交流过程中扮演了一个重要的角色:帮助提升细胞存活度。
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