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产品中心-北京博奥森生物技术有限公司
Recombinant Human SNX9 Protein, N-His (bs-102755P)  
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20ug/980.00元
50ug/1880.00元
100ug/2680.00元
大包装/询价
产品编号 bs-102755P
英文名称 Recombinant Human SNX9 Protein, N-His
中文名称
别    名 SH3 and PX domain-containing protein 3A; SNX9; SH3PXD3A; Sorting nexin-9; SH3PX1; SH3 and PX domain-containing protein 1; Protein SDP1  
克 隆 号
理论分子量 42.43 kDa
性    状 Lyophilized
纯    度 >90% as determined by SDS-PAGE.
缓 冲 液 Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
保存条件 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Sorting nexin (SNX) proteins are members of a large family of hydrophilic PX (phospholipid-binding motif) domain-containing proteins that interact with a variety of receptor types. SNXs are widely expressed, although the tissue distribution of each SNX mRNA varies. The ability of SNXs to bind specific phospholipids, as well as their tendency to form protein-protein complexes, suggests a role for these proteins in cellular membrane trafficking and protein sorting. SNXs may also function specifically in pro-degradative sorting, internalization, endosomal recycling or simply in endosomal sorting. SNXs partially associate with cellular membranes, despite their hydrophilic nature. SNX9 resides in the cytosol where it influences the processing and trafficking of insulin receptors. The enzyme aldolase binds to and inactivates SNX9. Phosphorylation of SNX9 releases aldolase and frees SNX9 to recruit and activate Dynamin II, a neuronal phosphoprotein and a GTPase enzyme which mediates late stages of endocytosis in both neural and non-neural cells.

SWISS:
Q9Y5X1

Gene ID:
51429

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