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产品中心-北京博奥森生物技术有限公司
Recombinant Human CNOT6 Protein, N-His (bs-102681P)  
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20ug/980.00元
50ug/1880.00元
100ug/2680.00元
大包装/询价
产品编号 bs-102681P
英文名称 Recombinant Human CNOT6 Protein, N-His
中文名称
别    名 KIAA1194; CCR4; CNOT6; CCR4a; CCR4 carbon catabolite repression 4-like; Cytoplasmic deadenylase; Carbon catabolite repressor protein 4 homolog; CCR4-NOT transcription complex subunit 6  
克 隆 号
理论分子量 48.37 kDa
性    状 Lyophilized
纯    度 >90% as determined by SDS-PAGE.
缓 冲 液 Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
保存条件 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 CNOT6 is a widely expressed subunit of the CCR4-NOT transcription complex. The CCR4-NOT complex is an evolutionarily conserved, multi-component complex known to be involved in transcription as well as mRNA degradation. Various subunits (e.g. CNOT1, CNOT3) are involved in influencing nuclear hormone receptor activities. The CCR4-NOT complex is also involved in the regulation of Histone H3 lysine 4 methylation through a ubiquitin-dependent pathway that likely involves the proteasome. CNOT6 belongs to the CCR4/nocturin family and contains three LRR (leucine-rich) repeats. In the cytoplasm, CNOT6 acts as a poly(A) nuclease involved in mRNA decay mediated by the major-protein-coding determinant of instability (mCRD) of the Fos gene.

SWISS:
Q9ULM6

Gene ID:
57472

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