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产品中心-北京博奥森生物技术有限公司
Recombinant Human APPL1 Protein, N-His (bs-102669P)  
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20ug/980.00元
50ug/1880.00元
100ug/2680.00元
大包装/询价
产品编号 bs-102669P
英文名称 Recombinant Human APPL1 Protein, N-His
中文名称
别    名 APPL1; Dip13-alpha; APPL; DIP13A; DCC-interacting protein 13-alpha; KIAA1428; Adapter protein containing PH domain; PTB domain and leucine zipper motif 1  
克 隆 号
理论分子量 32.33 kDa
性    状 Lyophilized
纯    度 >90% as determined by SDS-PAGE.
缓 冲 液 Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
保存条件 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. [provided by RefSeq, Jul 2008]

SWISS:
Q9UKG1

Gene ID:
26060

衔接因子蛋白含pH域磷酸酪氨酸结合域和亮氨酸拉链基元1抗体. APPL1可调节脂联素和胰岛素信号,是细胞膜与细胞核之间重要的信息传递蛋白,同时也是细胞增殖所必需的蛋白,它有调节脂联素在脂肪酸氧化和葡萄糖吸收中的作用,APPL1通过激酶通道来调节脂联素的胰岛素敏感效应。
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