| 产品编号 | bs-102597P |
| 英文名称 | Recombinant Human SPHK1 Protein, N-His |
| 中文名称 | |
| 别 名 | SPHK; SK 1; SPK; Acetyltransferase SPHK1; Sphingosine kinase 1; SPHK1; SPK 1; SK1 |
| 克 隆 号 | |
| 理论分子量 | 28.65 kDa |
| 性 状 | Lyophilized |
| 纯 度 | >90% as determined by SDS-PAGE. |
| 缓 冲 液 | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| 保存条件 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011] SWISS: Q9NYA1 Gene ID: 8877 SPHK1参与鞘氨醇代谢、G蛋白偶联受体蛋白信号转导途径，有抗细胞凋亡的作用，可被蛋白激酶C激活，参与细胞内信号转导级联、钙介导信号转导、调控细胞生长迁移、调控血管生成及成纤维细胞增殖。 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
