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Recombinant Human FOXP1 Protein, N-His (bs-102501P)  
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20ug/980.00元
50ug/1880.00元
100ug/2680.00元
大包装/询价
产品编号 bs-102501P
英文名称 Recombinant Human FOXP1 Protein, N-His
中文名称
别    名 FOXP1; MFH; Forkhead box protein P1; Mac-1-regulated forkhead  
克 隆 号
理论分子量 26.04 kDa
性    状 Lyophilized
纯    度 >90% as determined by SDS-PAGE.
缓 冲 液 Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
保存条件 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene(s). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

SWISS:
Q9H334

Gene ID:
27086

Hox程序的信息输出并有调节运动神经元功能。FoxP1在Hox敏感型运动柱中表达,使FoxP1失活能消除运动神经元Hox网络的信息输出,并将脊髓运动系统回复到原始状。 FoxP1的减少同样改变运动神经元连结性模式, 肢体运动神经似乎会随机选择目标肌肉和作用路径。单个的FoxP1转录因子能以Hox辅助因子的形式整合各种神经元种类的连结性。 Hox蛋白:哺乳动物的同源盒基因由61个氨基酸残基组成的蛋白质保守结构域,称同源异型域。Hox基因在动物体的体节结构分化等空间信息调控中起着重要作用,按特
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