| 产品编号 | bs-102377P |
| 英文名称 | Recombinant Human LRIG1 Protein, N-His |
| 中文名称 | |
| 别 名 | LIG-1; Leucine-rich repeats and immunoglobulin-like domains protein 1; LIG1; LRIG1 |
| 克 隆 号 | |
| 理论分子量 | 41.16 kDa |
| 性 状 | Lyophilized |
| 纯 度 | >90% as determined by SDS-PAGE. |
| 缓 冲 液 | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| 保存条件 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
LRIG1 protein is coded by a gene on a chromosome band 3p14.3, a region known to be deleted in various human cancers. It is considered to be a tumour suppressor gene. LRIG1 is an integral cell-surface membrane protein that is expressed by specific cells in various human tissues. Its 143kDa form may be cleaved into 111kDa and 32kDa fragments. The protein may inhibit the growth of tumors of glial cells and the down-regulation of the LRIG1 gene may be involved in the development and progression of the tumor. SWISS: Q96JA1 Gene ID: 26018 LRIG1属于LRIGs基因家族。LRIGs是新发现的一类基因，在哺乳动物体内广泛存在，目前发现该家族至少包括三个成员：LRIG1、LRIG2和LRIG3，是一类结构相似的跨膜糖蛋白，该蛋白人、鼠的同源性较高。 目前在肿瘤方面的研究较多，有研究认为：LRIG1是通过下调EGFR的表达来抑制其下游重要信号传导通路的激活而发挥抑癌作用，LRIG1在抑制肿瘤转移中具有重要作用。< |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
