产品编号 |
bs-41274P |
英文名称 |
Recombinant MERS-CoV N protein, N-His
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中文名称 |
重组MERS冠状病毒核蛋白 |
别 名 |
A0A0D3MU51_MERS; Nucleoprotein · Middle East respiratory syndrome-related coronavirus (MERS-CoV); MERS冠状病毒核衣壳蛋白; |
理论分子量 |
48.2 kDa |
检测分子量 |
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性 状 |
Liquid |
物 种 |
MERS-CoV |
序 列 |
1-423/423 |
纯 度 |
>90% by SDS-PAGE |
活性 |
Not tested |
标签 |
His Tag |
缓 冲 液 |
20mM Tris, 10% Glycerol. |
保存条件 |
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
注意事项 |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
产品介绍 |
Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.
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产品图片 |
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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