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FUT8 Rabbit pAb (bs-24389R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-24389R
英文名称 FUT8 Rabbit pAb
中文名称 岩藻糖转移酶8抗体
别    名 alpha(1, 6) fucosyltransferase; alpha-(1; alpha1 6FucT; alpha1-6FucT; Fucosyltransferase 8(alpha(1, 6) fucosyltransferase); Fucosyltransferase 8; FUT8; FUT8_HUMAN; GDP fucose glycoprotein fucosyltransferase; GDP L Fuc:N acetyl beta D glucosaminide alpha1,  
研究领域 肿瘤  细胞生物  免疫学  信号转导  肿瘤细胞生物标志物  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse,Rat (predicted: Human,Rabbit,Chicken,Dog,Horse)
产品应用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 66 kDa
检测分子量
细胞定位 细胞浆 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FUT8 : 201-300/575 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans.The expression of this gene may contribute to the malignancy of cancer cells and to their invasive and metastatic capabilities. There are 2 isoforms produced by alternative splicing. Immunogen is not present in isoform 2 (also known as Retinal).

Function:
Catalyzes the addition of fucose in alpha 1-6 linkage tocthe first GlcNAc residue, next to the peptide chains in N-glycans.

Subcellular Location:
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein.

Similarity:
Belongs to the glycosyltransferase 23 family.
Contains 1 SH3 domain.

SWISS:
Q9BYC5

Gene ID:
2530

Database links:
Entrez Gene: 2530 Human

Entrez Gene: 53618 Mouse

Entrez Gene: 432392 Rat

Omim: 602589 Human

SwissProt: Q9BYC5 Human

SwissProt: Q9WTS2 Mouse

SwissProt: Q6EV76 Rat

Unigene: 654961 Human

Unigene: 35628 Mouse

Unigene: 1717 Rat


产品图片
Sample: Lane 1: Lung (Mouse) Lysate at 40 ug Lane 2: Lung (Rat) Lysate at 40 ug Primary: Anti-FUT8 (bs-24389R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 66 kD Observed band size: 70 kD
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