| 产品编号 | bsm-63189R |
| 英文名称 | Rabbit Anti-phospho-GSK3 beta (S9) antibody |
| 中文名称 | 磷酸化糖原合酶激酶-3β重组兔单抗 |
| 别 名 | glycogen synthase kinase 3 beta; GSK-3 beta; GSK3B; GSK3beta isoform. |
| 抗体来源 | Rabbit |
| 克隆类型 | Recombinant |
| 交叉反应 | Human |
| 产品应用 | WB=1:1000-1:5000,IHC-P=1:100-1:200,IHC-F=1:100-1:200,IF=1:50-1:200,ICC/IF=1:50-1:200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 47kDa |
| 检测分子量 | 46 |
| 性 状 | Liquid |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human GSK3 beta around the phosphorylation site of S9 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| 保存条件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 产品介绍 |
Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), EIF2B, CTNNB1/beta-catenin, APC, AXIN1, DPYSL2/CRMP2, JUN, NFATC1/NFATC, MAPT/TAU and MACF1.Requires primed phosphorylation of the majority of its substrates. 激酶和磷酸酶（Kinases and Phosphatases） GSK3β是一个serine/threonine,proline 直接激酶，参与多个信号通路的排列，包括糖原合成和细胞黏附，GSK3β与AD病有关。此抗体识别分子量为47kDa 的GSK-3β蛋白。 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
