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Rabbit Anti-Adiponectin receptor protein 1  antibody (bsm-63149R)  
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说明书: 25ul  50ul  100ul  
25ul/800.00元
50ul/1400.00元
100ul/2500.00元
大包装/询价
产品编号 bsm-63149R
英文名称 Rabbit Anti-Adiponectin receptor protein 1  antibody
中文名称 脂联素受体1重组兔单抗
别    名 Adiponectin receptor protein 1; Progestin and adipoQ receptor family member I ; CGI-45; PAQR1; ADIPOR1.  
抗体来源 Rabbit
克隆类型 Recombinant
交叉反应 Human,Mouse,Rat
产品应用 WB=1:1000-1:2000,IHC-P=1:100-1:200,IHC-F=1:100-1:200,IF=1:50-1:200,Flow-Cyt=1:20-1:100,ICC/IF=1:50-1:200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 43kDa
检测分子量 43
性    状 Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human Adiponectin receptor protein 1 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
保存条件 Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
PubMed PubMed
产品介绍 Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism.Required for normal glucose and fat homeostasis and for maintaining a normal body weight. ADIPOQ-binding activates a signaling cascade that leads to increased AMPK activity, and ultimately to increased fatty acid oxidation, increased glucose uptake and decreased gluconeogenesis. Has high affinity for globular adiponectin and low affinity for full-length adiponectin.

脂联素与受体结合后具有增强胰岛素敏感性,抗高血糖,抗动脉粥样硬化等生物学效应,任何增加或减少脂联素及其受体表达的方法都影响这些疾病的发生和发展. 脂联素受体-1(AdipoR1和AdipoR2)同属于PAQR家族,具有七次跨膜蛋白的特有结构, mol wt:41kDa
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