| 产品编号 | D51082 |
| 英文名称 | ABT-888 dihydrochloride |
| 中文名称 | |
| 别 名 | PARP1/PARP2抑制剂 |
| 克 隆 号 | |
| CAS | 912445-05-7 |
| 理论分子量 | 317.21 kDa |
| 检测分子量 | |
| 性 状 | Lyophilized |
| 保存条件 | Store in dry, dark place for one year. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
ABT-888 dihydrochloride, also known asVeliparib, is a potent and selective Poly (ADP-Ribose) Polymerase (PARP) Inhibitor. ABT-888 dihydrochloride enhances apoptosis and autophagy in response to treatments that cause DNA breaks, including radiation and DNA alkylation. ABT-888 dihydrochloride is an orally bioavailable inhibitor of PARP1 and PARP2 (Kis = 5.2 and 2.9 nM, respectively). CAS号：912445-05-7 分子式：C13H16N4O 分子量：244.296 纯度：≥99% 溶解性：溶于DMSO 作用靶点：PARP; Autophagy 作用通路：Cell Cycle/DNA Damage; Epigenetics; Autophagy; 描述：维利帕尼二盐酸盐 (Veliparib dihydrochloride) 是有效的 PARP1 和 PARP2 抑制剂，Ki 分别为5.2 nM，2.9 nM。 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
