| 产品编号 | D50957 |
| 英文名称 | RS-1 |
| 中文名称 | |
| 别 名 | RAD51激活剂和CRISPR编辑增强剂 |
| 克 隆 号 | |
| CAS | 312756-74-4 |
| 理论分子量 | 524.23 kDa |
| 检测分子量 | |
| 性 状 | Lyophilized |
| 保存条件 | Store in dry, dark place for one year. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
RS-1 was previously characterized as a RAD51-Stimulatory compound and now found to be an HDR enhancer to enhance CRISPR/Cas9- and TALEN-mediated knock-in efficiency. It increases the knock-in efficiency by two- to five-fold at different loci, whereas NHEJ inhibitor SCR7 has minimal effects. RS-1 was applied for animal production and have achieved multifold improvement on the knock-in rates as well. RS-1 can stimulate the human homologous recombination protein RAD51in various conditions. In PC3 prostate cancer cells, RS-1–induced lethality was accompanied by the formation of microscopically visible RAD51 nuclear protein foci occurring in the absence of any DNA-damaging treatment. Treatment with RS-1 promoted significant antitumor responses in a mouse model. |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
