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SR9243 (D50928)  
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2mg/580.00元
10mg/1880.00元
大包装/询价
产品编号 D50928
英文名称 SR9243
中文名称
别    名   LXR Inverse激动剂
克 隆 号
CAS 1613028-81-1
理论分子量 626.62 kDa
检测分子量
性    状 Lyophilized
保存条件 Store in dry, dark place for one year.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 SR9243 is a potent and selective LXR inverse agonist. SR9243 kills cancer cells by inhibiting lipid production and the Warburg effect. SR9243 induces cell death in multiple types of cancer and does not cause the side effects that have derailed previous attempts to target these processes. In cancer cells, SR9243 significantly inhibited the Warburg effect and lipogenesis by reducing glycolytic and lipogenic gene expression. SR9243 induced apoptosis in tumors without inducing weight loss, hepatotoxicity, or inflammation. Malignant cells exhibit aerobic glycolysis (the Warburg effect) and become dependent on de novo lipogenesis, which sustains rapid proliferation and resistance to cellular stress.

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